Indications For Use:
NuStat® is a single-use hemostatic wound dressing applied externally with mechanical compression to temporarily control bleeding in lacerations, punctures, abrasions, surgical wounds (operative, postoperative, dermatological, etc.) and traumatic injuries.
Click here for the NuStat Flex® XR Indications and Instructions For Use Guide.
NuStat Flex® XR Instructions For Use2
C. Caleb Butts, Kelly Bose, M. Amin Frotan, Juvonda Hodge, Salil Gulati
Department of Surgery, University of South Alabama, United States
Results: For dressings used to treat the burn site, blood loss on the side treated with NuStat® was on average less (27g/100cm2) than the side treated with our historic standard of care (31g/100cm2), though it was not statistically significant (p=0.81).
Similarly, on the donor site, blood loss on the side treated with NuStat® was on average less (14g/100cm2) than the side treated with our historic standard of care (15g/100cm2), but it was also not statistically significant (p=0.92). Average total blood loss from both excision and donor sites was also less with NuStat® (10g/100cm2) compared to the historic standard of care (12g/100cm2), but it was also not significant (p=0.77). There was no difference in the number of cycles required to achieve hemostasis for either the burn (1.15 NuStat® vs. 1.1 for historic standard of care, p=0.70) or the donor site (1 vs. 1, p=1.0). When comparing the cost of NuStat® versus the historic standard of care, the actual costs incurred for the wounds was less for the portion treated with NuStat®
($148.43) when compared to the historic standard of care ($186.45) (p<0.001).
Conclusions: Based on these findings, NuStat® hemostatic agents should be comparable to the historic standard of care, and these newer hemostatic agents evaluated further in burn surgery and bleeding during other procedures such as trauma surgery.
Link to PubMed Article can be found here.
Activated platelets on cellulose fibers
Activated platelets on silica based fibers
NuStat Flex® XR is made from a blend of highly effective, non-impregnated, cellulose and silica-based hemostatic fibers. The cellulose fibers promote the contact activation pathway of the coagulation cascade by absorbing blood fluids, resulting in the localized concentration of platelets and clotting factors.
NuStat Flex® XR requires no preparation, are durable, absorbent, easy to apply and control bleeding rapidly. NuStat Flex® XR contains no coatings, latex or animal proteins.
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1. Evaluation of NuStat®, a Novel Nonimpregnated Hemostatic Dressing, Compared With Combat Gauze™ in Severe Traumatic Porcine Hemorrhage Model, Genevieve R. Hillis, BME, DO; Crystal J. Yi, DO; David L. Amrani, PhD, FAHA, FAIMBE; Troy W. Akers, DO; Richard Schwartz, MD, FACEP; Ian Wedmore, MD, FACEP, FAWM, DiMM; John G. McManus, MD, MBA, MCR, FACEP, FAAEM.
2. NuStat Trauma Pad® XR Instructions For Use
3. Data on File, Beeken Biomedical, Stoughton, MA